Clinical trials showing conditions with overall positive evidence for homeopathy

Listed below are  28 medical conditions in which there is currently a positive balance of evidence for homeopathy in randomised placebo-controlled trials (RCTs).

For complete details of these research studies in homeopathy, visit the Homeopathy Research Institute website.

Clearly positive:

Hay fever 1–8
Sinusitis 9-12

Tentatively positive:

Allergic skin reaction 13
Arsenic toxicity 14–17
Brain injury 18
Bronchitis 19
Childhood diarrhoea 20-23
Female infertility 25, 26
Fibromyalgia 27
Influenza 28, 29
Insomnia 30-32
Menopausal syndrome 33
Otitis media (acute) 34
Perrenial allergic rhinitis 35
Plantar fasciitis 36
Postpartum bleeding 37
Postpartum lactation 38
Premenstrual syndrome 39
Psoriasis 40
Radiodermatitis 41
Sepsis 42
Snoring 43
Stomatitis 44
Tonsillitis 45
Tracheal secretions 46
Uraemic pruritus 47
Varicose veins 48

References:

1 Aabel S, Laerum E, Dølvik S, Djupesland P  (2000). Is homeopathic ‘immunotherapy’ effective? A double-blind,  placebo-controlled trial with the isopathic remedy Betula 30c for  patients with birch pollen allergy. British Homeopathic Journal;  89:161–168.
2 Aabel S (2000). No beneficial effect of isopathic  prophylactic treatment for birch pollen allergy during a low-pollen  season: a double-blind, placebo-controlled clinical trial of homeopathic  Betula 30c. British Homeopathic Journal; 89:169–173.
3 Aabel S (2001). Prophylactic and acute treatment  with the homeopathic medicine Betula 30c for birch pollen allergy: a  double-blind, randomized, placebo-controlled study of consistency of VAS  responses. British Homeopathic Journal; 90:73–78.
4 Kim LS, Riedlinger JE, Baldwin CM, Hilli L,  Khalsa SV, Messer SA, Waters RF (2005). Treatment of seasonal allergic  rhinitis using homeopathic preparation of common allergens in the  southwest region of the US: a randomized, controlled clinical trial.  Annals of Pharmacotherapy; 39:617–624.
5 Reilly DT, Taylor MA, McSharry C, Aitchison T  (1986). Is homeopathy a placebo response? Controlled trial of  homeopathic potency, with pollen in hayfever as model. Lancet;  ii:881–885.
6 Wiesenauer M, Gaus W, Häussler S (1990).  Behandlung der Pollinoisis mit Galphimia glauca. Eine Doppelblindstudie  unter Praxisbedingungen [Treatment of pollinosis with the homeopathic  preparation Galphimia glauca. A double-blind trial in clinical  practice]. Allergologie; 13:359–363.
7 Wiesenauer M, Gaus W (1985). Double-blind trial  comparing the effectiveness of the homoeopathic preparation Galphimia  potentization D6, Galphimia dilution 10?6 and placebo on pollinosis.  Arzneimittel Forschung; 35:1745–1747.
8 Wiesenauer M, Lüdtke R (1995). The treatment of  pollinosis with Galphimia glauca D4 – a randomized placebo-controlled  double-blind clinical trial. Phytomedicine; 2: 3-6.
9 Friese K-H, Zabalotnyi DI (2007). Homöopathie bei  akuter Rhinosinusitis. Eine doppelblinde, placebokontrollierte Studie  belegt die Wirksamkeit und Verträglichkeit eines homöopathischen  Kombinations-arzneimittels [Homeopathy in acute rhinosinusitis. A  double-blind, placebo controlled study shows the efficiency and  tolerability of a homeopathic combination remedy]. HNO; 55:271–277.
10 Weiser M, Clasen B (1994). Randomisierte  plazebokontrolierte Doppelblindstudie zur Untersuchung der klinische  Wirksamkeit der homöopathischen Euphorbium compositum-Nasentropfen S bei  chronischer Sinusitis [Randomized, placebo-controlled, double-blind  study of the clinical efficacy of the homeopathic Euphorbium  compositum-S nasal spray in cases of chronic sinusitis]. Forschende  Komplementärmedizin; 1:251–259.
11 Zabolotnyi DI, Kneis KC, Richardson A,  Rettenberger R, Heger M, Kaszkin-Bettag M, Heger PW (2007). Efficacy of a  complex homeopathic medication (Sinfrontal) in patients with acute  maxillary sinusitis: a prospective, randomized, double-blind,  placebo-controlled, multicenter clinical trial. Explore (NY); 3:98–109.
12 Wiesenauer M, Gaus W, Bohnacker U, Häussler S  (1989). Wirksamkeitsprüfung von homöopathische Kombinationspräparaten  bei Sinusitis. Ergebnisse einer randomisierten Doppelblindstudie unter  Praxisbedingungen [Efficiency of homeopathic preparation combinations in  sinusitis. Results of a randomized double blind study with general  practitioners]. Arzneimittel Forschung; 39:620-625.
13 Naidoo P, Pellow J (2013). A randomized  placebo-controlled pilot study of Cat saliva 9cH and Histaminum 9cH in  cat allergic adults. Homeopathy; 102: 123-129.
14 Belon P, Banerjee A, Karmakar SR, Biswas SJ,  Choudhury SC, Banerjee P, Das JK, Pathak S, Guha B, Paul S,  Bhattacharjee N, Khuda-Bukhsh AR (2007). Homeopathic remedy for arsenic  toxicity? Evidence-based findings from a randomized placebo-controlled  double blind human trial. Science of the Total Environment; 384:141-50.
15 Khuda-Bukhsh AR, Pathak S, Guha B, Karmakar SR,  Das JK, Banerjee P, Biswas SJ, Mukherjee P, Bhattacharjee N, Choudhury  SC, Banerjee A, Bhadra S, Mallick P, Chakrabarti J, Mandal B (2005). Can  homeopathic arsenic remedy combat arsenic poisoning in humans exposed  to groundwater arsenic contamination? A preliminary report on first  human trial. Evidence-Based Complementary and Alternative Medicine;  2:537-548.
16 Belon P, Banerjee P, Choudhury SC, Banerjee A,  Biswas SJ, Karmakar SR, Pathak S, Guha B, Chatterjee S, Bhattacharjee N,  Das JK, Khuda-Bukhsh AR (2006). Can administration of potentized  homeopathic remedy, Arsenicum album, alter antinuclear antibody (ANA)  titre in people living in high-risk arsenic contaminated areas? I. A  correlation with certain hematological parameters. Evidence-Based  Complementary and Alternative Medicine; 3:99-107.
17 Khuda-Bukhsh AR, Banerjee A, Biswas SJ, Karmakar  SR, Banerjee P, Pathak S, Guha B, Haque S, Das D, De A, Das D,  Boujedaini N (2011a). An initial report on the efficacy of a millesimal  potency Arsenicum Album LM 0/3 in ameliorating arsenic toxicity in  humans living in a high-risk arsenic village. Journal of Chinese  Integrative Medicine / Zhong Xi Yi Jie He Xue Bao; 9: 596-604.
18 Chapman EH, Weintraub RJ, Milburn MA, Pirozzi  TO, Woo E (1999). Homeopathic treatment of mild traumatic brain injury: a  randomized, double-blind, placebo-controlled clinical trial. Journal of  Head Trauma Rehabilitation; 14: 521–542.
19 Diefenbach M, Schilken J, Steiner G, Becker HJ  (1997). Homöopathische Therapie bei Erkrankungen der Atemwege.  Auswertung einer klinischen Studie bei 258 Patienten [Homeopathic  therapy in respiratory tract diseases. Evaluation of a clinical study in  258 patients]. Zeitschrift für Allgemeinmedizin; 73:308–314.
20 Jacobs J, Jimenez LM, Gloyds SS, Gale JL,  Crothers D (1994). Treatment of acute childhood diarrhea with  homeopathic medicine; a randomized clinical trial in Nicaragua.  Pediatrics; 93:719–725.
21 Jacobs J, Jimenez LM, Malthouse S, Chapman E,  Crothers D, Masuk M, Jonas WB (2000). Homeopathic treatment of acute  childhood diarrhoea: results from a clinical trial in Nepal. Journal of  Alternative and Complementary Medicine; 6:131–139.
22 Jacobs J, Jiminez LM, Gloyds SS, Casares FE,  Gaitan MP, Crothers D (1993). Homoeopathic treatment of acute childhood  diarrhoea. A randomized clinical trial in Nicaragua. British  Homoeopathic Journal; 82:83–86.
23 Jacobs J, Guthrie BL, Montes GA, Jacobs LE,  Mickey-Colman N, Wilson AR, DiGiacomo R (2006). Homeopathic combination  remedy in the treatment of acute childhood diarrhea in Honduras. Journal  of Alternative and Complementary Medicine; 12:723–732.
24 Weatherley-Jones E, Nicholl JP, Thomas KJ, Parry  GJ, McKendrick MW, Green ST, Stanley PJ, Lynch SP (2004). A randomized,  controlled, triple-blind trial of the efficacy of homeopathic treatment  for chronic fatigue syndrome. Journal of Psychosomatic Research;  56:189–197.
25 Bergmann J, Luft B, Boehmann S, Runnebaum B,  Gerhard I (2000). Die Wirksamkeit des Komplexmittels Phyto-Hypophyson® L  bei weiblicher, hormonell bedingter Sterilität. Eine randomisierte,  plazebokontrollierte, klinische Doppelblindstudie [The efficacy of the  complex medication Phyto-Hypophyson L in female, hormone-related  sterility. A randomized, placebo-controlled clinical double-blind  study]. Forschende Komplementärmedizin und Klassische Naturheilkunde;  7:190–199.
26 Gerhard I, Pateck A, Monga B, Blank A, Gorkow C  (1998). Mastodynon bei weiblicher Sterilitat. Randomisierte,  plazenbokontrollierte, klinische oppelblindstudie. [Mastodynon for  female infertility. Randomised, placebo controlled, clinical  double-blind study]. Forschende Komplementärmedizin; 5:272-278.
27 Bell I, Lewis D, Brooks A, Schwartz G, Lewis S,  Walsh B, Baldwin C (2004). Improved clinical status in fibromyalgia  patients treated with individualized homeopathic remedies versus  placebo. Rheumatology; 43:577–582.
28 Ferley JP, Zmirou D, D’Adhemar D, Balducci F  (1989). A controlled evaluation of a homoeopathic preparation in the  treatment of influenza like syndromes. British Journal of Clinical  Pharmacology; 27:329–335.
29 Papp R, Schuback G, Beck E, Burkard G, Bengel J,  Lehrl S, Belon P (1998). Oscillococcinum® in patients with  influenza-like syndromes: a placebo-controlled double-blind evaluation.  British Homoeopathic Journal; 87:69–76.
30 Kolia-Adam N, Solomon E, Bond J, Deroukakis M  (2008). The efficacy of Coffea cruda on insomnia: a double blind trial.  Simillimum; 21: 91-99.
31 Naudé DF, Couchman IMS, Maharaj A (2010).  Chronic primary insomnia: efficacy of homeopathic simillimum.  Homeopathy; 99:63–68. [Published erratum: Homeopathy 2010; 99: 151]
32 Harrison CC, Solomon EM, Pellow J (2013). The  effect of a homeopathic complex on psychophysiological onset insomnia in  males: a randomized pilot study. Alternative Therapies in Health and  Medicine; 19:38-43.
33 Colau JC, Vincent S, Marijnen P, Allaert FA  (2012). Efficacy of a non-hormonal treatment, BRN-01, on menopausal hot  flashes: a multicenter, randomized, double-blind, placebo-controlled  trial. Drugs in R&D;12:107-119.
34 Jacobs J, Springer DA, Crothers D (2001).  Homeopathic treatment of acute otitis media in children: a preliminary  randomized placebo-controlled trial. Pediatric Infectious Disease  Journal; 20:177–183.
35 Taylor MA, Reilly D, Llewellyn-Jones RH,  McSharry C, Aitchison TC (2000). Randomised controlled trial of  homoeopathy versus placebo in perennial allergic rhinitis with overview  of four trial series. British Medical Journal; 321:471–476.
36 Clark J, Percivall A (2000). A preliminary  investigation into the effectiveness of the homeopathic remedy, Ruta  graveolens, in the treatment of pain in plantar fasciitis. British  Journal of Podiatry; 3:81–85.
37 Oberbaum M, Galoyan N, Lerner-Geva L, Singer SR,  Grisaru S, Shashar D, Samueloff A (2005). The effect of the homeopathic  remedies Arnica and Bellis perennis on mild postpartum bleeding – a  randomized, double-blind, placebo-controlled study – preliminary  results. Complementary Therapies in Medicine; 13:87–90.
38 Berrebi A, Parant O, Ferval F, Thene M, Ayoubi  JM, Connan L, Belon P (2001). Traitement de la douleur de la montée  laiteuse non souhaitée par homéopathie dans le postpartum immédiat  [Treatment of pain due to unwanted lactation with a homeopathic  preparation given in the immediate post-partum period]. Journal de  gynécologie, obstétrique et biologie de la reproduction; 30:353–357.
39 Yakir M, Kreitler S, Brzezinski A, Vithoulkas G,  Oberbaum M, Bentwich Z (2001). Effects of homeopathic treatment in  women with premenstrual syndrome: a pilot study. British Homeopathic  Journal; 90:148–153.
40 Bernstein S, Donsky H, Gulliver W, Hamilton D,  Nobel S, Norman R (2006). Treatment of mild to moderate psoriasis with  Reliéva, a Mahonia aquifolium extract – a double-blind,  placebo-controlled study. American Journal of Therapeutics; 13:121-126.
41 Balzarini A, Felisi E, Martini A, De Conno F  (2000). Efficacy of homeopathic treatment of skin reactions during  radiotherapy for breast cancer: a randomized, double-blind clinical  trial. British Homeopathic Journal; 89:8–12.
42 Frass M, Linkesch M, Banyai S, Resch G,  Dielacher C, Lobl T, Endler C, Haidvogl M, Muchitsch I, Schuster E  (2005). Adjunctive homeopathic treatment in patients with severe sepsis:  a randomized, double-blind, placebo-controlled trial in an intensive  care unit. Homeopathy; 94:75–80.
43 Lipman D, Sexton G, Schlesser J (1999). A  randomized double-blind placebo-controlled evaluation of the safety and  efficacy of a natural over-the-counter (OTC) medication in the  management of snoring. Sleep and Breathing; 3: 53-56.
44 Oberbaum M, Yaniv I, Ben-Gal Y, Stein J, Ben-Zvi  N, Freedman LS, Branski D (2001). A randomized, controlled clinical  trial of the homeopathic medication Traumeel S in the treatment of  chemotherapy-induced stomatitis in children undergoing stem cell  transplantation. Cancer; 92:684–690.
45 Malapane E, Solomon EM, Pellow J (2014).  Efficacy of a homeopathic complex on acute viral tonsillitis. Journal of  Alternative and Complementary Medicine; 20:868-873.
46 Frass M, Dielacher C, Linkesch M, Endler C,  Muchitsch I, Schuster E, Kaye A (2005). Influence of potassium  dichromate on tracheal secretions in critically ill patients. Chest;  127:936–941.
47 Cavalcanti AM, Rocha LM, Carillo R Jr, Lima LU,  Lugon JR (2003). Effects of homeopathic treatment on pruritus of  haemodialysis patients: a randomized placebo-controlled double-blind  trial. Homeopathy; 92:177–181.
48 Ernst E, Saradeth T, Resch KL (1990).  Complementary therapy of varicose veins – a randomized,  placebo-controlled, double-blind trial. Phlebology; 5:157–163.